What is Urethra & Urethral Stricture?

• The urethra is the tube that carries urine from the bladder to outside of the body.
• The length of urethra is 15 to 20 cm for men and 3 to 4 cm for women.
• Narrowing of the urethral tube is known as Urethral Stricture.

Current Standard of Care of Urethral Stricture

• Dilatation: Widening of the stricture
• Urethrotomy: Opening up of the fibrous tissue by endoscopic surgery.
• Urethroplasty: Using large buccal grafts (10 cm) and suturing at stricture site via open surgery.

Drawbacks of Currently Available Treatments

• A high rate of infection
• Irreversible damage to the entire urinary tract
• A high rate of disease recurrence
• Painful
• Highly invasive procedure
• Sexual and Erectile dysfunction
• Quality of Life affected
• Loss of Pay
• Societal taboo